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To find out whether the Pro32Pro33 mutation has an effect on the αvβthree receptor–SERT conversation in midbrain synapses, we done coimmunoprecipitation experiments.

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Our laboratory demonstrated that SERT and αvβthree receptors colocalize in midbrain presynaptic terminals (Mazalouskas et al., 2015), suggesting that SERT is localized to multiprotein complexes coordinated by integrin αvβthree in midbrain synapses. Prior experiments suggest that in platelets, the association of SERT with activated αIIbβthree integrins, and its localization to adhesion complexes, are correlated with elevated uptake action (Carneiro et al.

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Skeptics demand from customers a system by which this SNP could give increase to big dissimilarities in platelet perform. The short article by Vijayan et al. (2) In this particular challenge on Pro33 slot the JCI

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